Another update: Sadie went in on Wednesday again, things turned worse, she stopped eating again. This time she saw a different doc, our dr of choice at the u of m, he is top notch! Blood work came back not good, enzymes were lower but so were the things that the liver is supposed to produce. Cancer is not suspected, leptospirosis test was submitted and we are waiting for results(not really suspected though), they don't think it's cancer either. It could be toxins or canine hepatitis. To be sure a liver biopsy would need to be done which is not without it's risks, hemorrhaging and death. We decided after all the info to treat for hepatitis and hope and pray! Lots of antibiotics and steroids. So far she is improving slightly, hopefully that continues, we have a recheck on Wednesday.