I started a thread 6-8 months ago on here asking about the safety of Trifexis. Most called the claims that Trifexis wasn't safe BS. I had several back and forth PM's with a couple of well respected RTF vets and both defended Trifexis. I know one administered it to their dogs and I want to say both did. The common theme with both vets was "give with food" and everything will be fine. I've seen great results from it and thankfully, no side effects. I figured if these two vets, working for that elusive "N" that goes in front of FC/AFC in their dogs titles, were comfortable enough to give it to their animals then I shouldn't have a problem giving it to my "wanna be".
To the OP...sorry about your pup and glad things worked out.