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Thread: Trying to research some info on EIC

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    Senior Member BIG DOG's Avatar
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    Default Trying to research some info on EIC

    Carriers inparticular, I was wondering what if any the percentage of carriers having an episode is

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    Senior Member The Snows's Avatar
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    Carriers are not "affected", therefore no episodes. Carriers strictly carry the gene for EIC.
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    Senior Member Kevin Eskam's Avatar
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    EIC Clear = Will not collapse
    EIC Carrier = Will not collapse
    EIC Effected= Some will collapse and some will not.....
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    Senior Member BIG DOG's Avatar
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    Got a buddy who was telling me his dog who is a carrier, went down a couple months ago running blinds.
    It had me concerned a little since I to own a carrier, out of different lines


    Thanks guys!

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    Senior Member FOM's Avatar
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    Quote Originally Posted by BIG DOG View Post
    Got a buddy who was telling me his dog who is a carrier, went down a couple months ago running blinds.
    It had me concerned a little since I to own a carrier, out of different lines


    Thanks guys!
    I would gander that it might of been heat related if the dog was tested and it was for sure he was a carrier.
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    Senior Member Sundown49 aka Otey B's Avatar
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    Quote Originally Posted by Kevin Eskam View Post
    EIC Clear = Will not collapse
    EIC Carrier = Will not collapse
    EIC Effected= Some will collapse and some will not.....
    Right on ....
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    Senior Member 3blackdogs's Avatar
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    Quote Originally Posted by Kevin Eskam View Post
    EIC Clear = Will not collapse
    EIC Carrier = Will not collapse
    EIC Effected= Some will collapse and some will not.....
    Having very first hand knowledge about EIC and also watching what Jeff is tracking, I would suggest that the last entry should be "EIC AFFECTED - Most will collapse, research underway as to why some do not".

    But I sure wouldn't gamble on that "most" modifier for the sake of breeding and, more importantly, the well-being of the dog.
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    Senior Member BIG DOG's Avatar
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    Little more info. The breeder had the pups tested before they went home, his was a carrier. After his dog went down he had it tested and he came back a carrier as well. Weather could have played a part but I'm not sure, from my understanding the dog went down early spring/ late winter. But we have weird weather in ne tx. Snow 1 day, swimming the next type weather lol.

    Is there another lab that test for eic besides the U of Mn?

    I've owned 4 dogs that were affected, it's a heart breaking sight to watch them have an episode.

    The Yellow pup in my avatar is affected

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    U of MN developed the test and I would not trust any of the other labs to run the test.

    If the dog tested "carrier" after the event, then something else caused the collapse. Could have been heat related, could be heart, could be a lot of things.

    Meredith

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    Senior Member frontier's Avatar
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    Quote Originally Posted by 3blackdogs View Post
    Having very first hand knowledge about EIC and also watching what Jeff is tracking, I would suggest that the last entry should be "EIC AFFECTED - Most will collapse, research underway as to why some do not".

    But I sure wouldn't gamble on that "most" modifier for the sake of breeding and, more importantly, the well-being of the dog.
    Here's the AKC Health Foundation link for the information on the ongoing EIC research on EIC:

    "Once the test was available, however, it quickly became clear that the existence of the DNM1 mutation didn’t explain all cases of EIC in the breed. Some Labrador Retrievers with EIC didn’t have both copies of the mutation, others didn’t have copies at all. Therefore, the scientists from the University of Minnesota and the University of Saskatchewan who had developed the test set out to determine if they could understand whether the EIC seen in dogs without the mutation was really the same condition as d-EIC."
    http://www.akcchf.org/research/succe...nding-EIC.html

    Also, University of Minnesota has a link describing the differences between EIC and several of the other conditions often confused with EIC.
    http://www.vdl.umn.edu/ourservices/c...2008/home.html



    I also only trust University of Minnesota Diagnostic Lab for EIC DNA tests, and OFA still currently only accepts EIC results from University of Minnesota for their health database
    Last edited by frontier; 07-10-2014 at 03:57 PM.
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