Make no mistake about it. Bedbugs are EVERYWHERE now. I'm not even close to kidding about that.
The best tip that I can give you, is about how to find them before you get bit. You will NEVER see them or their signs on the bed itself.
The staff will keep the bed clean and change the sheets daily (usually).
But, they don't mess with the headboard.
In a hotel, the headboard hangs on the wall like a picture. Take it off the wall, and lay it on the bed.
Then, take a flashlight and shine it in all the cracks and crevices that are normally in complete darkness.
If there's a CURRENT bedbug problem, you will see live adult and juvenile bedbugs.
If there WAS a problem, you will see shed skins, eggshells, and possibly dead adult and juvenile bedbugs.
In my experience, there aren't many hotels that haven't ever had a bedbug problem. Even the "ritzy" ones. But, it's like a hooker with an STD. If they talk about it, they immediately lose all of their clientele.
At least there are some, that have the decency to fix the problem, before taking in a new "tenant".