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Thread: Interesting Picture from the 2019 NRC

  1. #11
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    It is not a genetic issue cannot be passed on pursuant to my question to a vet.
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  3. #12
    Senior Member Bryan Parks's Avatar
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    Quote Originally Posted by moscowitz View Post
    It is not a genetic issue cannot be passed on pursuant to my question to a vet.
    There is a gene however within purebred labs than can cause this mismark and can be passed on. K-locus I believe

    https://www.pawprintgenetics.com/pro...s/details/164/
    Last edited by Bryan Parks; 11-15-2019 at 06:25 PM.
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    Quote Originally Posted by drunkenpoacher View Post
    Cool looking dog.
    What are the odds of a lab with that condition/coloring making it to the NRC?
    Small! No doubt about that. Haha. Very cool though. What are the odds of ANY Labrador making it to the NRC let alone one with that coloring. Cool.

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    Has this chimera bitch ever been bred? Just curious as to whether anything is known about her fertility.

    As I understand, chimeras can have fertility issues if the egg/fetus merger was one of male/female. Has anyone done any studies on fertility of chimeras in Labradors? I've heard that calico and tortoiseshell cats have a higher percentage of infertility than average. Is it the same in dogs?

  7. #15
    Junior Member MSW's Avatar
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    Since a chimera is an embryonic fusion of two separate group of cells which would have developed into two different puppies, the genotype would depend on where the dna was extracted. The phenotype is the expression of the gene, in this case that would be the color.
    Last edited by MSW; 11-17-2019 at 10:29 PM.
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  8. #16
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    Sometimes a chimera has one DNA type in blood and another DNA type in the organs/reproductive tract. There are some fascinating cases in people where women almost had their kids taken away because the initial DNA test indicated the kids weren't theirs...

    https://en.m.wikipedia.org/wiki/Lydia_Fairchild

    There may be more canine chimeras than we realize, but they aren't identified because black on black is still black, not the neat yellow and black pattern seen on Mystic.
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  9. #17
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    Here is a great article with pictures, about the various mis-marks that can occur in Labradors. This dog is a Chimera. I have a friend that bred one. She came into heat normally, as to fertility, she was never bred. http://www.blueknightlabs.com/mismarks/index.html
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    She is probably not a chimera, which would be a fusion of two embryos. Her color is more likely to be an example of a somatic pigment mutation. Somatic pigment cells in the embryo mutated. From what I've read, none of the "blotched" dogs whose DNA has been tested have been shown to be chimera, although they have been found in other species.

    A couple of websites with more info and a few photos:

    http://www.doggenetics.co.uk/oddities.html

    http://color.ashgi.org/color/Aussie_...mutations.html

    Mystic would not pass the patchiness on to her offspring.
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  11. #19
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    [QUOTE=PalouseDogs;2184040]

    Thank you for the fabulous links. I had not seen the story about Spotty, the somatic cell lab.

    Fascinating that the first site speculates the yellow/red genes might be more unstable thus subject to mutation more easily.

    Do any Labrador retrievers carry the recessive black gene?

  12. #20
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    Thanks for these explaining, I saw her too and was wondering if it was a shadow.
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