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Thread: Pro Heart 6/12

  1. #11
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    Quote Originally Posted by EdA View Post
    A reminder for those who use ProHeart for heartworm prevention, there is no protection from intestinal parasites as there is in most of the oral monthly preventatives. Regular fecal exams are recommended.
    Thanks Dr. Eda! I’m still on the fence. I have a new pup that I will be having to make the decision in a couple of months.

    I can however say that in the 5 years that I have been giving my pack the heart guard I have had zero parasites of any kind.

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  3. #12
    Senior Member Swack's Avatar
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    Quote Originally Posted by Steve Shaver View Post
    Been using it for a few years. I assume it works but heartworm is not all that common here. I love not having to remember heartguard once a month. I get an email from my vet telling me when they are due. That's one reason I switched but the main is in the picture below. While cleaning up the morning after giving heartguard I found the whole thing had passed straight through the dog. Havent used heartguard since.
    Attachment 80882Attachment 80882
    Steve,

    If you read the insert that comes in the package for Heartgard Plus, it states that the product should be given in a manner which encourages that dog to chew the product OR to break it up into pieces for dogs that tend to swallow treats whole, which is what I do.

    I've wondered if the trend toward ivermectin resistance in heartworms is due to people who give this product whole. Their dogs could assimilate less ivermectin than the recommended dose which may kill the more sensitive heartworms, but those which survive are the ones that tend to be more resistant. Theoretically, over time this could result in a resistant strain of heartworm.

    Just an observation and a thought.

    Swack
    Jeff Swackhamer

  4. #13
    Senior Member Don Smith's Avatar
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    I used Proheart 6 or awhile, but switched because there didn't seem to be any evaluation of effect on fertility of a breeding bitch. I'd appreciate your input Dr. Ed.
    HRCH Meglyn's Maramaxx Daisycutter MH-30 (Daisy)
    SHR Meglyn's Eye on the Prize JH (Molly)
    Meglyn's Timbrhuntn ValleyGirl (Lilly)
    Meglyn's Prime Time to Leave Me Lucille SH (Lucy)
    Meglyn's Lionheart MH (Little Guy)
    Meglyn-Firemark's I am NOT a Lab SH (Goldie)
    Meglyn's Lil Miss Sureshot SH CGCA(Annie)
    In memory of Chevy, HR Meglyn's Silverado Slim SH, July 20, 2006, HR Meglyn's Blue Ridge Belle MH, July 19, 2008 and HRCH Meglyn's Honest Abe MH, Aug 9, 2013.

    www.meglynretrievers.com

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  6. #14
    Senior Member EdA's Avatar
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    ANIMAL SAFETY
    General Safety: ProHeart 6 has been administered to a wide variety of healthy dogs six months of age and older, including a wide variety of breeds, pregnant and lactating females, breeding males, and ivermectin-sensitive collies. In clinical studies, two geriatric dogs with a history of weight loss after the initial ProHeart 6 injection died within a month of the second 6 month injection. A third dog who was underweight for its age and breed and who had a history of congenital problems experienced lethargy following the initial injection of ProHeart 6. The dog never recovered and died 3 months later

    This is from the manufacturer.

    You can weigh that against my personal objection to foreign substances in the body on a permanent basis. Repository injections of drugs are sometimes life saving and needed. I do not view heartworm prevention in that way. Heartworm prevention is based on destroying the tissue phase larvae at a specific time in it’s developmental cycle. The drugs are given at specific intervals, they kill the larvae, and they are excreted from the body or metabolized. Moxidectin in microencapsulation remains in the body continuously until the microencapsulation vehicle degrades. No one knows what the long term effects of that might be. Perhaps it is innocuous and benign but that is something we do not know. Proheart would not be on my approved list for breeding age bitches for whatever that is worth.
    Last edited by EdA; 02-13-2020 at 07:46 PM.

  7. #15
    Senior Member Don Smith's Avatar
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    Quote Originally Posted by EdA View Post
    ANIMAL SAFETY
    General Safety: ProHeart 6 has been administered to a wide variety of healthy dogs six months of age and older, including a wide variety of breeds, pregnant and lactating females, breeding males, and ivermectin-sensitive collies. In clinical studies, two geriatric dogs with a history of weight loss after the initial ProHeart 6 injection died within a month of the second 6 month injection. A third dog who was underweight for its age and breed and who had a history of congenital problems experienced lethargy following the initial injection of ProHeart 6. The dog never recovered and died 3 months later

    This is from the manufacturer.

    You can weigh that against my personal objection to foreign substances in the body on a permanent basis. Repository injections of drugs are sometimes life saving and needed. I do not view heartworm prevention in that way. Heartworm prevention is based on destroying the tissue phase larvae at a specific time in it’s developmental cycle. The drugs are given at specific intervals, they kill the larvae, and they are excreted from the body or metabolized. Moxidectin in microencapsulation remains in the body continuously until the microencapsulation vehicle degrades. No one knows what the long term effects of that might be. Perhaps it is innocuous and benign but that is something we do not know. Proheart would not be on my approved list for breeding age bitches for whatever that is worth.
    Thanks, Dr. Ed!
    HRCH Meglyn's Maramaxx Daisycutter MH-30 (Daisy)
    SHR Meglyn's Eye on the Prize JH (Molly)
    Meglyn's Timbrhuntn ValleyGirl (Lilly)
    Meglyn's Prime Time to Leave Me Lucille SH (Lucy)
    Meglyn's Lionheart MH (Little Guy)
    Meglyn-Firemark's I am NOT a Lab SH (Goldie)
    Meglyn's Lil Miss Sureshot SH CGCA(Annie)
    In memory of Chevy, HR Meglyn's Silverado Slim SH, July 20, 2006, HR Meglyn's Blue Ridge Belle MH, July 19, 2008 and HRCH Meglyn's Honest Abe MH, Aug 9, 2013.

    www.meglynretrievers.com

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