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Cheque (mibolerone) drops for delaying estrus in bitches is available from Wedgewood Pharmacy 800-331-8272 to licensed veterinarians. They require a copy of your the veterinarians current DEA registration certificate. It is packaged in 55 ml bottles containing 120 mcg/ml. The dose for dogs 51-100 lbs is 1.2 ml once daily beginning 30 days prior to the onset of the next anticipated heat cycle.