I do it all the time. Take a look at the product review page under Ainley Deerskin link. My box is built in two pieces where the box and drawer are actually separate. The drawers bolt to the bed and the box bolts to the drawers.
Deerskin put 4 d-rings on the box and the drawers, I use tiedown straps I can adjust to get the box or drawers out while level. I had an i-beam mounted in the shop and went to Harbor Freight and bought a hoist and trolley, it takes about 10 minutes to take in and out.
If I could I would suggest you bolt it in the bed a huge bump or an accident could be tragic.
Deerskin put 4 d-rings on the box and the drawers, I use tiedown straps I can adjust to get the box or drawers out while level. I had an i-beam mounted in the shop and went to Harbor Freight and bought a hoist and trolley, it takes about 10 minutes to take in and out.
If I could I would suggest you bolt it in the bed a huge bump or an accident could be tragic.