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Discussion Starter · #1 ·
TVD (Tricuspid Valve Dysplasia) in Labradors was a big topic a couple years ago and seems to have been more quiet recently. Is it still mostly unknown about how/if it is inherited? Thoughts on cardiac testing? Thoughts in general on TVD?
 

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I was told by someone that is in contact with those doing the study that TVD is an autosomal recessive disorder similar to EIC or CNM (takes two carriers and/or affected dogs to produce an affected dog). Take that with a grain of salt - It’s second hand information.
 

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Not a simple autosomal recessive. Not clearly mapped or identified in Labradors or any other breed at this point.

Meredith
 

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Not a simple autosomal recessive. Not clearly mapped or identified in Labradors or any other breed at this point.

Meredith
That article is from 2018. The information I was told was from the progression of the study and is more recent. Like I said, it's second hand information.
 

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Discussion Starter · #5 ·
I was told by someone that is in contact with those doing the study that TVD is an autosomal recessive disorder similar to EIC or CNM (takes two carriers and/or affected dogs to produce an affected dog). Take that with a grain of salt - It’s second hand information.
I have also heard that two clear dogs (clear by cardiac echo) have produced carriers and affected dogs. Seems hard to identify
 

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I do know that I'm seeing more Echos being listed with OFA particularly with FC-AFC type stud dogs
 

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I m not a vet and the only degree I have is from the school of hard knocks !
Does the OFA or CHF have a definitive test for TVD in our retriever breeds.
Yes I had Fancy done with a cardiac test via a specialist and I have a paper with an all clear
However if I understood correct there is no guideline for what machine to use or how it’s interpreted. Am I wrong here !
 

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You can oscillation (just listening) or Echo. Echo is the standard because just listening cannot always pick up subtle problems/damage. So the trick is to only use dogs that have had Echos. Much like hips and elbows, we are looking at phenotype, not genotype.

Meredith
 

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TVD (Tricuspid Valve Dysplasia) in Labradors was a big topic a couple years ago and seems to have been more quiet recently. Is it still mostly unknown about how/if it is inherited? Thoughts on cardiac testing? Thoughts in general on TVD?
Interested parties were holding their breath awaiting results from the latest study that was going on at NCSU. Unfortunately the results have not been promising as far as developing a test, it looks like there is more than one gene involved in causing the defect, this is what the lead researcher (Dr. Kate Meurs) said a few months ago. This was said in a Good Dog Symposium webinar in Sept 2021 that has not had a transcript produced of it yet or I would post the excerpt. So, this is a situation like with hip dysplasia where we just have to keep checking breeding stock for it (via echo because auscultation misses cases of it), and cross our fingers it doesn't show up in the pups...
 

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I had an echo done 2 1/2 years ago on my male. He was graded a 1/5 for TVD. It’s very minor but was advised to not sire him. Cardiologists said they really aren’t sure if it’s passed on or not.
TVD (Tricuspid Valve Dysplasia) in Labradors was a big topic a couple years ago and seems to have been more quiet recently. Is it still mostly unknown about how/if it is inherited? Thoughts on cardiac testing? Thoughts in general on TVD?
 
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